Looking for a comforting, old-fashioned chicken and biscuits recipe that won't weigh you down? This easy chicken biscuit casserole is a family-favorite weeknight dinner that brings classic Southern comfort right to your table.
Made with lean chicken breast, low-sodium cream of mushroom soup, and a reduced-fat biscuit topping, it delivers all the rich flavor of grandma's cooking in a lighter, one-pan meal. It's the perfect low-calorie chicken casserole for a cozy night in!
Whether you're cooking for a crowd or meal-prepping for the week, this diabetic-friendly dish fits perfectly into a balanced lifestyle. Check out more healthy meal ideas in our heart healthy chicken dinner collection!
This delicious, one-pan comfort meal swaps heavy saturated fats and excess sodium for lean poultry and a smart soup substitution. By utilizing a reduced-fat biscuit mix and plenty of mixed vegetables, it delivers the creamy, hearty texture of a traditional bake while staying perfectly aligned with your wellness goals.
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You can easily swap in low-sodium cream of chicken soup if you prefer that flavor. It will give the casserole a slightly richer poultry taste while maintaining the same creamy texture and healthy profile.
The easiest method is to use a store-bought reduced-fat biscuit mix, as called for in this recipe. Just blend it with skim milk and parsley, shape into rounds, and place them directly on the hot casserole to bake.
Be sure to add the biscuit dough only during the final baking stages rather than from the beginning. When storing leftovers, keep the biscuits in a separate airtight container at room temperature, while refrigerating the chicken filling.
If you loved the warm, comforting flavors of our chicken and biscuit bake, you will also enjoy these other cozy, protein-packed chicken dinners that are perfect for chilly weeknights.
For more simple, one-pan meals that deliver old-fashioned flavor without the extra calories, explore these easy, heart-healthy chicken casseroles and bakes.
Recipe yields 6 servings
Preheat oven to 400°. Lightly coat a baking sheet with nonstick cooking spray. Chop chicken breasts into 1-inch cubes and transfer to baking sheet. Bake for 15 minutes, or until chicken is cooked through.
Lightly coat a 9-inch pie plate with nonstick cooking spray and add cubed chicken, onion, celery, water, mixed vegetables, soup and thyme. Place in oven.
In a bowl, combine biscuit mix, milk and parsley. Mix until blended. With lightly floured hands form dough into 6 biscuits.
Remove chicken and soup mixture from oven and place uncooked biscuits on top of mixture. Return to oven for an additional 10 minutes or until biscuits are lightly golden. Reduce oven temperature to 350° and bake for an additional 10 to 15 minutes.
If you prefer a crispier biscuit or want to avoid heating up the whole oven, you can bake the reduced-fat biscuits separately on a baking sheet according to package directions. Meanwhile, simmer the chicken, vegetables, and soup mixture on the stovetop in a large skillet over medium-low heat until the chicken is fully cooked and the sauce thickens. Serve the hot chicken filling ladled over the freshly baked biscuits.
Since this easy chicken biscuit casserole is quite rich and filling on its own, it pairs beautifully with light, fresh side dishes. A crisp, leafy green salad with a citrus vinaigrette helps cut through the creaminess of the mushroom soup. Alternatively, serving it alongside sautéed green beans, roasted Brussels sprouts, or a refreshing Kale Crunch Salad rounds out the meal perfectly while keeping it heart-healthy.
As mentioned, a low-sodium cream of chicken or cream of celery soup works perfectly if you aren't a mushroom fan. There are also unsalted versions of these soups if you need to lower the sodium content even more.
You can use leftover shredded cooked chicken or cooked turkey breast to save time; simply skip the initial 15-minute chicken baking step.
Any unsweetened, plain plant-based milk (like almond or oat milk) can be substituted in the biscuit dough if you need a dairy-free option.
Feel free to swap the frozen mixed veggies for fresh chopped carrots, peas, and green beans, just ensure they are par-boiled slightly so they cook evenly in the bake.
For more ways to turn chicken into family-friendly meals that are healthy, check out these other chicken recipes for dinner. High in protein and low in fat, chicken is the ultimate healthy meat to enjoy over and over again, as long as you come up with different ways to cook it so you don’t get bored. You may also want to look over these easy chicken dinner ideas and chicken meal prep for more inspiration.