Heart Healthy Strawberry Orange Smoothie

(5.0)
By Judy Capodanno
Updated 11/18/2025
Dietitian Reviewed: Jane Schwartz, RDN, CLT
Approved for These Diets:
Heart Healthy | Gluten Free | Diabetic | Vegetarian
Heart Healthy Strawberry Orange Smoothie
Photo Credit: Adobe Stock

This heart-healthy, low-fat strawberry orange smoothie is the perfect light and refreshing start to your day. It’s naturally sweet, thanks to the combination of citrus, strawberries, and a sneaky addition of cantaloupe: a trick to add volume and fiber without a lot of extra calories. Not only is this recipe approved for heart-healthy and diabetic diets, but it’s also packed with vitamin C and protein from the nonfat Greek yogurt, making it a powerful, low-calorie way to stay full and boost your immune health. See more healthy smoothie recipes here.

Total Time
10 minutes
Servings
4
Calories
93

What Makes These Strawberry Orange Smoothies Healthy

This smoothie is an excellent choice for a low-calorie, low-fat meal replacement or snack. By using nonfat Greek yogurt and no added sugar, we maximize protein and calcium while keeping the overall glycemic load low, making it a fantastic option for diabetic and heart-healthy eating plans.

Key Health Highlights

  • Heart Health Support: Low in saturated fat and sodium, aligning with dietary recommendations for cardiovascular wellness.
  • High in Vitamin C: Strawberries and oranges are loaded with Vitamin C, essential for immune function and antioxidant protection.
  • Good Source of Protein: The inclusion of nonfat plain Greek yogurt provides a significant protein boost to aid in satiety and muscle maintenance.
  • Increased Fiber: Cantaloupe and strawberries contribute dietary fiber, supporting digestive health and helping to regulate blood sugar levels.
  • Bone Health: Utilizes calcium-fortified orange juice and Greek yogurt, providing two key sources of calcium for strong bones.
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FAQs About Strawberry Orange Smoothies

Yes, the combination is delicious! The natural acidity of the orange juice complements the sweetness of the strawberries perfectly.

For a thicker smoothie, reduce the amount of ice or use frozen cantaloupe. For a creamier texture, substitute a few tablespoons of the orange juice with a non-dairy milk alternative (like unsweetened almond milk).

You can mix the ingredients (except the ice) and store them in a freezer-safe bag or container overnight. When ready to serve, simply blend with the required ice and enjoy.

More Heart-Healthy Low-Calorie Smoothies

Low-Calorie Fruit Smoothies

These easy smoothies are bursting with fresh flavor and perfect for a weight-loss diet.

Heart Healthy Mixed Berry Smoothie
Heart Healthy Blueberry Banana Smoothie
Heart Healthy Green Smoothie
Heart Healthy Strawberry Peach Smoothie

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Easy Recipes for Busy Weekdays

Reach for these tasty, simple recipes that can be prepared in minutes, keeping you on schedule and your health goals on track.

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Ingredients

Recipe yields 4 servings

Directions

  1. In a blender, purée orange juice and cantaloupe. Add yogurt, strawberries and ice and blend until smooth. Serve topped with orange slices, if desired.

Nutrition Facts

Serving Size:
1 cup

93
Calories
1
g
Fat
0
mg
Cholesterol
40
mg
Sodium
21
g
Carbs
0
g
Sat. Fat
2
g
Fiber
4
g
Protein

Serving & Storage Tips

This smoothie is best consumed immediately after blending for the creamiest texture and maximum nutrient retention. If storing leftovers, pour the smoothie into an airtight container and refrigerate for up to 24 hours; note that it will separate, so stir well before serving. For a cool treat, pour the blended mixture into popsicle molds and freeze.

Ingredient Substitutions

If you need a lower-sugar or lower-sodium option, you can use fresh-squeezed orange juice mixed with water (or even low-sodium club soda for fizz), but you will lose the calcium fortification.

For a dairy-free option, use an unflavored, unsweetened soy or coconut-based yogurt alternative. Ensure your choice is low in added sugars to maintain the diabetic-friendly nature of the recipe.

Consider blending in 1 scoop of unflavored or vanilla-flavored whey or plant-based protein powder.

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